OVERVIEWContinuing discoveries in molecular biology, genetics, and process science provide the foundation for new and improved processes and products in today's biochemical process industry. The production of therapeutic proteins, which is made possible by discoveries in biotechnology, generated sales exceeding $1. In addition, biotechnology has led to marked improvement and expansion in the traditional biochemical process industry for production of enzymes, diagnostics, chemicals, pharmaceuticals, and foods. Continued introduction of new technology necessitates innovation in process development scale- up and design. As a consequence, there is the need to design new, as well as to improve existing, processes. An integral and cost intensive part of these processes is associated with downstream processing for product isolation and purification.
Takeways from this course include: Understanding the fundamentals of downstream processing for biochemical product recovery. Assessing the impact of change in unit's operations and the impact on the process. Examining traditional unit operations, as well as new concepts and emerging technology that is likely to benefit biochemical product recovery in the future. Analyzing both analytical and process validation issues that are critical to successful manufacturing, focusing on large- scale, high- purity protein production. Examining strategies for biochemical process synthesis. Addressing centrifugation, chromatography, filtration, membrane processes, an introduction to continuous processing, process economics, process synthesis and simulation, and regulatory issues and validation. Who should attend: The course covers fundamental principles of downstream processing with practical examples and case studies to illustrate the problems and solutions faced by the practitioner. It is intended to provide both insight into and an overview of downstream processing for individuals actively engaged in process research and development, as well as those who manage and innovate in the biochemical process industry. Increasingly, scientists and engineers engaged in fermentation and cell culture development attend the course to better understand the context of the whole process. Attendees include: Engineers and scientists interested in design, economics, validation optimization and scale- up of biochemical product recovery; Protein biochemists and chemists involved in design of recovery processes; Managers responsible for biochemical process development; Entrepreneurs, attorneys, and business leaders seeking an overview and insight into biochemical manufacturing. Downstream Processing Of Proteins Pdf ReaderMost, if not all, proteins examined in the laboratory or industrially produced on a large scale need to be purified. Downstream Processing Of Proteins Methods And Protocols. 29-08-2016 2/2 Downstream Processing Of Proteins Methods And Protocols. Other Files Available to Download Downstream Processing.
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December 2016
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